A. de Cózar Group

2021

2020

(72) Effect of Remote Substituents on the Torquoselectivity of 3-Silyl Cyclobutene-Derivatives Ring-Opening

       Reactions

       Olatz Larrañaga, Abel de Cózar*

      ChemPhysChem 2020, 21, 1805–1813.








     

(71) Nitroprolinates as nucleophiles in Michael-type additions and acylations. Synthesis of enantiomerically

       enriched fused amino- pyrrolidino-[1,2-a]pyrazinones and -diketopiperazines

       Eduardo García-Mingüens, Verónica Selva, Olatz Larrañaga, Carmen Nájera, José M. Sansáno,* Abel de Cózar*

      ChemCatChem 2020, 12, 2014–2021.

(81) Biological properties and conformational studies of ambiphilic Pd(I) and Ni(II) complexes bearing

       functionalized aroylaminocarbo-N-thiopyrrolinate units

      Samet Poyraz, Samet Belveren, Sabriye Aydinoglu, Mahmut Ulger, Abel de Cózar, Maria de Gracia Retamosa,

      José M. Sansano, H. Ali Dondas*

      Belstein J. Org. Chem. 2021, 17, 2812–2821.










(80)  Additive and Emergent Catalytic Properties of Dimeric Unnatural Amino Acid Derivatives:  

       Aldol and Conjugate Additions

       Maria de Gracia Retamosa, Andrea Ruiz-Olalla, Maddalen Agirre, Abel de Cózar, Tamara Bello, Fernando P.

       Cossío *

     Chem. Eur. J. 2021, 27, 15671–15687.









(79) Structure, isomerization and dimerization processes of naringenin flavonoids

       Ana González Moreno,* Pilar Prieto, M. Carmen Ruiz Delgado, Eva Dominguez, Antonio Heredia,* Abel de Cózar*

      Chem. Phys. Phys. Chem. 2021, 23, 18068–18077.









(78) Controlling the molecular arrangement of racemates through weak interactions: the synergy

       between p-interactions and halogen bonds

       Carlos Romero–Nieto,* Abel de Cózar,* Elzbieta Regulska, John B. Mullenix, Frank Rominger, Philip Hindenberg  

      Chem. Commun. 2021, 57, 7366–7369.









(77) Doping Platinum with Germanium: An Effective Way to Mitigate the CO Poisoning

       Andoni Ugartemendia, Kristien Peeters, Piero Ferrari, Abel de Cózar, José M. Mercero, Ewald Janssens,* Elisa

       Jimenez–Izal*

      ChemPhysChem 2021, 22, 1603–1610.









(76) syn-Selective Michael Reaction of α-Branched Aryl Acetaldehydes with Nitroolefins Promoted by

       Squaric Amino Acid Derived Bifunctional Brønsted Bases

       Ane García-Urricelqui, Abel de Cózar, Teresa E. Campano, Antonia Mielgo,* Claudio Palomo*

     Eur. J. Org. Chem. 2021, 3604–3612.










(75) Synthesis of b-hydroxy a-Aminoacids Through Brønsted Base-Catalized syn-selective Direct Aldol

       Reaction of Schiff Bases of Glycine o-Nitroanilide

       Silvia Vera, Ana Vázquez, Ricardo Rodriguez, Sandra del Pozo, Iñaqui Urruzuno, Abel de Cózar, Antonia Mielgo,*

       Claudio Palomo*

      J. Org. Chem. 2021, 86, 7757–7772.









(74) Nature of Alkali- and Coinage-Metal Bonds versus Hydrogen Bonds

       Olatz Larrañaga, Ana Arrieta, Célia Fonseca-Guerra, F. Matthias Bickelhaupt,* Abel de Cózar*

      Chem. Asian J. 2021, 16, 315–321.








     

(73) Probing a-Amino Aldehydes as Weakly Acidic Pronucleophiles: Direct Access to Quaternary a-Amino  

       Aldehydes by an Enantioselective Michael Addition Catalyzed by Brønsted Bases

      Ane García-Urricelqui, Abel de Cózar, Antonia Mielgo,* Claudio Palomo*

       Chem. Eur. J.  2021, 27, 2483–2492.

2022

(85) Does the composition in PtGe cluster play any role in fighting CO poisoning?

      Andoni Ugartemendia, José M. Mercero,* Abel de Cózar, Elisa Jimenez-Izal*

      J. Chem. Phys. 2022, 156,174301–11 .








(84) Radiationless mechanism of UV deactivation by cuticle phenolics in plants

      Ana González Moreno, Abel de Cózar,* Pilar Prieto, Eva Domínguez, Antonio Heredia*

      Nature Comm. 2022, 13, 1786–1797 ("Plants and agriculture" Editors' Highlights page).









(83) Triarylamine enriched Organostannoxane Drums: Synthesis, Optoelectrochemical Properties,  

       Association Studies, and Gelatiin Behavior

       Silvia Collavini,* Sebastian F. Völker, Andrea Cabrera-Espinoza, Manuel A. Martinez,  Abel de Cózar,

       Leire San Felices, Luis Sanchez,* Juan Luis Delgado*

      Inorg. Chem. 2022, 61, 4046–4055.









(82) Role of Imine Isomerization in the Stereocontrol of the Staudinger Reaction between Ketenes and

        Imines

       Fernando P. Cossío,* Abel de Cózar, Miguel A. Sierra,* Luis Casarrubios, Jaime G. Muntaner, Bimal K. Banik,*

       Debasish Bandyopadhyay

      RSC Adv. 2022, 12, 104–117.

     

2014

(46) Regio and diastereoselective multicomponent 1,3-dipolar cycloadditions between prolinate

       hydrochlorides, aldehydes and dipolarophiles for the direct synthesis of pyrrolizidines

       Juan Mancebo-Aracil, Carmen Nájera,* Luis M. Castelló, José M. Sansano,* Olatz Larrañaga, Abel de Cózar,

       Fernando P. Cossío

      Tetrahedron 2015, 71, 9645–9661.


(45) Resonance driven regioselective demethylation of berberine. Microwave assisted synthesis of

       berberrubine and its assessment as fluorescent chemosensor for alkanes

       Arantzazu Delgado-Camón, Carmen Jarne, Vicente L. Cebolla,* Olatz Larrañaga,  Abel de Cózar, Fernando P.

       Cossío, Yosu Vara, Andrés Domñinguez, Luis Membrado, Javier Galbán, Rosa Garriga

        Tetrahedron 2015, 71, 6148–6154.


(44) Enantioselective Synthesis of exo-4-Nitroprolinates from Nitro- alkenes and Azomethine Ylides Catalyzed by

       Chiral Phosphor- amidite·Silver(I) or Copper(II) Complexes

       Luis M. Castelló, Carmen Nájera, José M. Sansano,*  Olatz Larrañaga, Abel de Cózar, Fernando P. Cossío

      Synthesis 2015, 47, 934–943.


(43) Synthesis of Chromen[4,3-b]pyrrolidines by Intramolecular 1,3-Dipolar Cycloadditions of Azomethine

       Ylides: An Experimental and Computational Assessment of the Origin of Stereocontrol

       Paulo R. R. Costa, José M. Sansano,* Unai Cossío, Julio, C. F. Barcellos, Ayres G. Días, Carmen Nájera, Ana

       Arrieta,  Abel de Cózar, Fernando P. Cossío*

      Eur. J. Org. Chem.  2015, 4689–4698.


(42) Remote Substituent Effects on the Stereoselectivity and Organocatalytic Activity of Densely Substituted

       Unnatural Proline Esters in Aldol Reactions

       María de G. Retamosa, Abel de Cózar, Mirian Sánchez, José I. Miranda, José M. Sansano, Luis M. Castelló,

       Carmen Nájera, Ana I. Jiménez, Francisco J. Sayago, Carlos Cativiela, Fernando P. Cossío*,

       Eur. J. Org. Chem.  2015, 2503–2516.


(41) Azobenzene-functionalized iridium(III) triscyclometalated complexes

       Jorge Pérez-Miqueo, Ainara Telleira, Martín Muñoz-Olasagasti, Ainhoa Altube, Eva García-Lecina, Abel de Cózar,

       Zoraida Freixa*

      Dalton Trans. 2015, 44, 2075–2091.


(40) Synthesis of radiolabelled aryl azides from diazonium salts: experimental and computational results

        permit the identification of the preferred mechanism

        Sarmeer M. Joshi, Abel de Cózar, Vanessa Gómez-Vallejo, Jacek Koziorowski, Jordi Llop,* Fernando P. Cossío*

        Chem. Commun. 2015, 51, 8954–8957.


(39) Is it possible to achieve a complete desaturation of cycloalkanes promoted by o-benzyne?

       Francisco Cervantes-Navarro, Abel de Cózar, Fernando P. Cossío,* María A. Fernandez-Herrera, Gabriel Merino,*

       Israel Fernandez*

      Chem. Commun. 2015, 51, 5302–5305.


(38) Azobenzene-Appended Bis-Cyclometalated Iridium(III) Bipyridyl Complexes

        Ainara Telleira, Jorge Pérez-Miqueo, Ainhoa Altube, Eva García-Lecina, Abel de Cózar, Zoraida Freixa*

       Organometallics 2015, 34, 5513–5529.

     

2015

(54) Taniaphos AgF-catalyzed enantioselective 1,3-dipolar cycloaddition of stabilized azomethine ylides

       derived from 2,2-dimethoxyacetaldehyde

       Alberto Cayuelas, Olatz Larrañaga, Carmen Nájera, José M. Sansano,* Abel de Cózar, Fernando P.

       Cossío*

      Tetrahedron 2016, 72, 6043–6051.


(53) Cyclopropanation reactions catalysed by dendrimers possessing one metalloporphyrin active site at the

       core: linear and sigmoidal kinetic behaviour for different dendrimer generations

       Petr Vins, Abel de Cózar, Iván Rivilla, Katerina Novakova, Ronen Zangi, Josef Cvackz, Iosune Arrastia, Ana

       Arrieta, Pavel Drasar, José I. Miranda, Fernando P. Cossío*

        Tetrahedron 2016, 72, 1120–1131.


(52) Synthesis of Chiral Spiro-nitroprolinates by Silver(I) Catalysis

       Alberto Cayuelas, Ricardo Ortiz, Carmen Nájera, José M. Sansano,* Olatz Larrañaga, Abel de Cózar, Fernando P.

       Cossío*

      Synfacts 2016, 12, 0819.


(51) New Insights into the Reactivity of Cisplatin with Free and Restrained Nucleophiles: Microsolvation

       Effects and Base Selectivity in Cisplatin–DNA Interactions

        Abel de Cózar, Olatz Larrañaga, F. Matthias Bickelhaupt, Eider San Sebastian, Elisabeth Ortega-Carrasco, Jean

        -Didier Maréchal, Agustí Lledós, Fernando P. Cossío*

       ChemPhysChem  2016, 17, 3932–3947.


(50) Enantioselective Synthesis of Polysubstituted Spiro-nitroprolinates Mediated by a

      (R,R)‐Me-DuPhos·AgF-Catalyzed 1,3-Dipolar Cycloaddition

       Alberto Cayuelas, Ricardo Ortiz, Carmen Nájera, José M. Sansano,* Olatz Larrañaga, Abel de Cózar, Fernando P.

       Cossío*

      Org. Lett. 2016, 18, 2926–2929.


(49) Ion-Pair SN2 Substitution: Activation Strain Analyses of Counter- Ion and Solvent Effects

        Jalal Z. A. Laloo, Lydia Rhyman, Ponadurai Ramasami,* F. Matthias Bickelhaupt,* Abel de Cózar*

        Chem. Eur. J. 2016, 22, 4431–4439.


(48) Alkenyl Arenes as Dipolarophiles in Catalytic Asymmetric 1,3-Dipolar Cycloaddition Reactions of

       Azomethine Ylides

       Ana Pascual Escudero, Abel de Cózar, Fernando P. Cossío,* Javier Adrio,* Juan C. Caretero*

       Angew. Chem. Int. Ed. 2016, 55, 15334–15338.

     

(47) Donor-Stabilized 1,3-Disila-2,4-diazacyclobutadiene with a Nonbonded Si···Si Distance Compressed to a

       Si=Si Double Bond Length

       David Gau, Raphael Nougué, Nathalie Saffon-Merceron,  Antoine Baceiredo, Abel de Cózar, Fernando P. Cossío,*

       Daisuke Hashizume, Tsuyoshi Kato,*  

      Angew. Chem. Int. Ed. 2016, 55, 14673–14677.

2016

(60) Diastereoselective [3 + 2] vs [4 + 2] Cycloadditions of Nitroprolinates with α,β-Unsaturated Aldehydes and

       Electrophilic Alkenes: An Example of Total Periselectivity

       Verónica Selva, Olatz Larrañaga, Luis M. Castelló, Carmen Nájera, José M. Sansano,*  Abel de Cózar*

      J. Org. Chem. 2017, 82, 6298–6312.


(59) Asymmetric identity SN2 transition states: Nucleophilic substitution at carbon and silicon centers

       Marucs V. J. Rocha, Nicole W. G. Smits, Lando P. Wolters, Abel de Cózar, Célia Fonseca Guerra, Teodorico C.

       Ramalho, F. Matthias Bickelhaupt*

       Int. J. Mass Spectros.  2017, 413, 85–91.


(58) Intramolecular SEAr Reactions of Phosphorus Compounds: Computational Approach to the Synthesis of

       p-Extended Heterocycles

       Olatz Larrañaga, Carlos Romero-Nieto,* Abel de Cózar*

      Chem. Eur. J. 2017, 23, 17487–17496.


(57) Mono- and Di-Alkylation Processes of DNA Bases by Nitrogen Mustard Mechlorethamine

        Olatz Larrañaga, Abel de Cózar,* Fernando P. Cossío

        ChemPhysChem 2017, 17, 3390–3401.


(56) A Guide for the Design of Functional Polyaromatic Organophosphorus Materials

       Philip Hindenberg, Alicia López-Andarias, Frank Rominger, Abel de Cózar,* Carlos Romero-Nieto*

      Chem. Eur. J. 2017, 23, 13919–13928.

     

(55) Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(II) and

        copper(II) complex

       Iván Rivilla, Abel de Cózar, Thomas Schäfer, Frank J. Hernandez, Alexander M. Bitner, Aitziber Eleta-Lopez, Ali

       Aboudzadeh, José I. Santos, José I. Miranda, Fernando P. Cossío,*

       Daisuke Hashizume, Tsuyoshi Kato,*  

      Chem. Sci. 2017, 8, 7038–7046.

(65) Alkaloids Reactivity: DFT Analysis of Selective Demethylation Reactions

        Olatz Larrañaga, José I. Miranda, Fernando P. Cossío* Abel de Cózar*

       J. Org. Chem.  2018, 83, 15105–15109


(64) Unnatural Amino Acid Ester Catalyzed Formal Synthesis of (+)-Pancracine

       María de G. Retamosa, Andrea Ruiz-Olalla, Tamra Bello, Abel de Cózar, Fernando P. Cossío*

      Synfacts 2018, 14, 0311.


(63) Cooperative Catalysis with Coupled Chiral Induction in 1,3-Dipolar Cycloadditions of Azomethine Ylides

        Alberto Cayuelas, Olatz Larrañaga, Verónica Selva, Carmen Nájera,* Takahiko Akiyama, José M. Sansano,*

        Abel de Cózar, José I. Miranda, Fernando P. Cossío*

        Chem. Eur. J. 2018, 24, 8092–8097.


(62) Ion-Pair SN2 Reaction of OH– and CH3Cl: Activation Strain Analyses of Counterion and Solvent Effects

       Jalal Z. A. Laloo, Lydia Rhyman, Olatz Larrañaga, Ponadurai Ramasami,* F. Matthias Bickelhaupt,* Abel de

      Cózar*

       Chem. Asian. J. 2018, 13, 1138–1147.

     

(61) Donor-Stabilized 1,3-Disila-2,4-diazacyclobutadiene with a Nonbonded Si···Si Distance Compressed to a

       Si=Si Double Bond Length

       María de G. Retamosa, Andrea Ruiz-Olalla, Tamra Bello, Abel de Cózar, Fernando P. Cossío*

      Angew. Chem. Int. Ed. 2018, 57, 668–672.

(70)  Design, synthesis and amplified spontaneous emission of 1,2,5-benzothiadiazole derivatives

        Raúl Martín,* Pilar Prieto,* José R. Carrillo, Ana M. Rodríguez, Abel de Cózar, Pedro C. Boj, María A.

        Díaz-García, Manuel G Ramírez*

       J. Mat. Chem. 2019, 7, 9996–10007.


(69) Switching Diastereoselectivity in Catalytic Enantioselective (3+2) Cycloadditions of Azomethine Ylides

        Promoted by Metal Salts and Privileged Segphos-Derived Ligands

       Guilherme S. Caleffi, Olatz Larrañaga, Marcos Ferrándiz-Saperas, Paulo R. R. Costa, Carmen Nájera,*

       Abel de Cózar, Fernando P. Cossío,* José M. Sansáno*

      J. Org. Chem. 2019, 84, 10593–10605.


(68) Dismantling the Hyperconjugation of p-Conjugated Phosphorus Heterocycles

        Olatz Larrañaga, Carlos Romero-Nieto,* Abel de Cózar*

        Chem. Eur. J. 2019, 25, 9035–9044.


(67) From bioactive pyrrolidino[3,4-c]pyrrolidines to more bioactive pyrrolidino[3,4-b]pyrrolidines via

       ring-opening ring-closing promoted by sodium methoxide

       Samet Belveren, Olatz Larrañaga, Samet Poyraz, H. Ali Dondas,* Mahmut Ülger, Ertan Sahin, Marcos

       Ferrándiz-Saperas, José M. Sansano,* Abel de Cózar*

       Synthesis 2019, 51, 1565–1577.

     

(66) Effect of an α-Methyl Substituent on the Dienophile on Diels-Alder endo:exo Selectivity

       Olatz Larrañaga, Abel de Cózar*

      ChemistryOpen 2019, 8, 49-57.

2019

2017

2018